Trigeminal trophic syndrome*
نویسندگان
چکیده
An Bras Dermatol. 2017;92(4):584-95. How to cite this article: Hayashida MZ, Pinheiro JRS, Enokihara MMSS, Vasconcellos MRA. Biologic therapy-induced pemphigus. An Bras Dermatol. 2017;92(4):591-3. Mailing address: Mônica Ribeiro de Azevedo Vasconcellos Av. Borges Lagoa, 508 -Vila Clementino 04038-000 -São Paulo, SP Brazil E-mail: [email protected] in adults.6 The metabolism of both drugs is still unknown.5 Biologic drugs can trigger immediate transfusion reactions and rarely induce the formation of cellular autoantibodies or even autoimmune conditions, such as lupus erythematosus, usually of late onset. The frequency of tocilizumab’s infusion reactions is around 7%; in a recent study with 226 infusions in individuals with autoimmune conditions, no immediate infusion reactions were observed. Nonetheless, it is still a medication with limited use.7 There are no reports of biologic drug-induced pemphigus until now. We highlight the importance of the dermatologist in the pharmacovigilance phase for new drugs. q
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Trigeminal trophic syndrome.
Ulceration of the nose may be inadvertently induced by the patient. Although trigeminal trophic syndrome is an uncommon cause of chronic ulcers, healthcare providers should consider the possibility of this disorder when encountering a patient with nasal ulcerations. Trigeminal trophic syndrome most commonly occurs in older women following therapy for trigeminal neuralgia. The ulcers usually inv...
متن کاملTrigeminal Trophic Syndrome: Report of 2 Cases
OBJECTIVE We present 2 cases of trigeminal trophic syndrome treated by surgery. METHODS We performed reconstruction of the ala nasi using a nasolabial flap or paramedian forehead flap in combination with an auricular chondrocutaneous composite graft. RESULTS One case was successfully treated. However, ulceration recurred intermittently in the other case. CONCLUSIONS Although trigeminal tr...
متن کاملAn atypical case of trigeminal trophic syndrome: A legal medicine perspective in medical responsibility
BACKGROUND Trigeminal trophic syndrome is a rare complication of peripheral or central damage to the trigeminal nerve characterized by anesthesia, paresthesia and a secondary persistent facial ulceration. METHODS We describe the case of a 40-year-old woman with previous history of Le Fort I osteotomy for a class III malocclusion who developed trigeminal trophic syndrome. Atypically, the cutan...
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Trigeminal trophic syndrome is an uncommon cause of facial ulcers, that affects the sensitive area of the trigeminal nerve. We present the case of an 84-year-old patient with ulcerated facial trigeminal trophic syndrome, and report the development of a clinico-dermoscopic approach for his clinical examination. The value of this model for the diagnosis of facial ulcers suspected to be a rodent u...
متن کاملTrigeminal trophic syndrome complicating a case of borderline tuberculoid leprosy.
An example of trigeminal trophic syndrome presenting as ulceration of ala nasi in a case of borderline tuberculoid leprosy is reported. To the best of our knowledge, this is only the second case report of this manifestation in leprosy to be documented.
متن کاملTreatment options in trigeminal trophic syndrome: a multi-institutional case series.
Trigeminal trophic syndrome (TTS) is an uncommon medical condition that may be encountered by otolaryngologists and facial plastic surgeons. TTS begins with damage to the trigeminal nerve or its central sensory connections, causing anesthesia in a dermatomal distribution. With repeated scratching and manipulation, an ulceration occurs, often in the alar region. In this multi-institutional repor...
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